During the sixties, Sporting reached a high point of European success in winning the Cup Winner's Cup in 1963/64 in a campaign lasting 3 games that saw a spectacular 5-0 win over Manchester United and a goal-fest against Apoel de Chipre: With Sporting winning 16-1, which is still the record for most goals scored in a European match. This victory engineered the Sporting management team, which few believed would be possible at the outset, was largely due to the togetherness and psychological strength of the team. A team led principally by Gentil Cardoso, later by the architect Anselmo Fernandez and other great names of "Lions" and national football such as Carvalho, Pedro Gomes, Lino Alexandre Batista, José Carlos, Hilário, Fernando Mendes (The Great Captain), Geo, Pérides, Osvaldo Silva, Figueiredo, Mascarenhas and João Morais: scorer of the infamous goal directly from a corner in Antwerp that would prove to be the winning goal of the competition.
 
With the ending of the Cup Winner's Cup after the 1998/99 season and its subsequent reshaping into the UEFA cup, Sporting became the only Portuguese club to win this historic title.
 
Between 1960 and 1999, Sporting's football team would win a further seven National Championships including the 1981/82 championship, and seven more Portuguese Cups, including the 1994/95 Cup: A victory that would mark the return to the top of the national podium after a prolonged absence. The juniors would also enjoy success: winning six championships, with the juvenile teams also winning eight titles. Sporting's children would also win three National Cups: A cup which ran during the nineties.
 
In 1974, with 46 goals, Hector Yazalde, Winger of Sporting, won the golden boot of the Champions of Europe. His record still stands to this day. In 2002, Mário Jardel became the second sporting player to win this European title of distinction.

In roller hockey, Sporting enjoyed a wave of success between 1965 and 1990: winning a European Champions Cup, which placed them as the best team in the world at the time, three Cup Winner’s Cups and one CERS Cup. The athletics teams of Sporting continued to enjoy success and were a constant source of pride for Sporting, with Carlos Lopes winning 3 cross country World Championships and one gold and one silver medal at Olympic level. The athletes of Sporting also guided the country to a victory in the marathon in the Los Angeles Olympics in 1984. The trophies won by these athletes formed a precursor to the other Olympic, World and European titles that Sporting can today boast.

Fernando Memede became the world record holder for the 10,000 metres, which was a record that stood for 5 years on the world level and an amazing 15 years as the European record.

In 2000, Sporting’s athletics team enjoyed success in the European Champions Clubs Cup on the track: making Portugal the only team to defeat Russia, who remains to this day as one of the athletics powers of the world. This glorious victory was further consolidated as Portugal finished third in three other events. These victories where further evidence of Sporting’s ability to maintain its Olympic athletes at the highest level: Confirming its place of excellence as one of Europe’s premier athletics clubs. Athletes such as Carlos Lopes, the Castro brothers, Fernando Mamede, all of whom are international medal and record winners, Rui Silva, Naide Gomes, Francis Obikwelu (Europe’s fastest man), Yuri Bilonog and Ionela Tirlea are all athletes of Sporting's centenary generation that expresses and interprets Sporting’s drive for success on all fronts.

In Handball, another Sport with a special place at the heart of Sporting, Sporting’s teams spurred to an amazing penta-championship between 1968/69 and 1972/73, a record still unbeaten in Portugal.
João Roque, Leonel Miranda, Joaquim Agostinho and Marco Chagas, among others, all shone in cycling in Portuguese as well as foreign events, with Agostinho achieving an impressive third place in the Tour de France, Second place in the Tour of Spain and three victories in the Tour of Portugal – dying on the 10th of May 1984 in a crash caused by a dog while he was racing in his yellow jacket in the Algarve on behalf of Sporting. His name is forever immortalised, as the epic climb of Alpe D’Huez in the Tour de France is now named after this infamous Portuguese cyclist and Sporting fan.

In table tennis, Sporting amassed a collection of national titles that is unbeatable. Between 1984-85 and 1994-95, the Lions won every single National Championship on offer - 11 in total.

In billiards, Sporting’s representatives also shone on the European levels in both individual and team events.